Система сверхвысокого разрешения, Lattice SIM 5, ZEISS

Super-Resolution Imaging System ZEISS Lattice SIM 5

ZEISS Lattice SIM 5 is a super-resolution microscopy system designed for high-speed live-cell imaging with uniform resolution in all spatial dimensions.

The system enables visualization of fast biological processes and subcellular dynamics with exceptional clarity. It combines Lattice SIM illumination with advanced SIM² reconstruction to achieve high spatial and temporal resolution while maintaining gentle imaging conditions.

Key Features

• Super-resolution imaging down to ~60 nm.
• High-speed acquisition up to 255 fps.
• Uniform resolution in XY and Z dimensions.
• Optimized for live-cell and dynamic process imaging.
• Flexible balance between resolution, speed, and light exposure.

Technologies

• Lattice SIM: light-efficient structured illumination for live imaging.
• SIM² reconstruction: enhanced resolution and artifact reduction.
• SIM Apotome: fast overview imaging before high-resolution acquisition.

Applications

• Live-cell imaging and fast biological processes.
• Subcellular structure and organelle dynamics.
• Protein interaction and intracellular transport.
• Single-cell analysis.
• Dynamic studies in living systems.

Advantages

• High temporal resolution: capture rapid cellular events.
• True live imaging: minimal phototoxicity and gentle conditions.
• Consistent detail: uniform super-resolution in all dimensions.
• Adaptability: optimize imaging for speed or detail.
• Reliable data: robust reconstruction with reduced artifacts.